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KMID : 1094020190360050274
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Journal of Veterinary Clinics
2019 Volume.36 No. 5 p.274 ~ p.277
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Successful Combination Chemotherapy for Nasal Carcinoma in a Dog
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Kim Su-Gang
Cho Seok-Ho
Kim Keon
Park Hee-Myung
Park Sang-Ik
Kim Tae-Jung
Lee Chang-Min
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Abstract
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A Miniature Schnauzer presented with bilateral mucopurulent nasal discharge and sneezing. Computed tomography of the skull revealed exudates in the nasal cavity and frontal gyrus. Nasal swab cytology showed features of an epithelial-origin tumor. Histopathologic evaluation of the biopsy specimen revealed irregular proliferation of epithelial cells and necrotized tissue. Positive immunohistochemical staining confirmed the epithelial origin of the cells. The dog was diagnosed with nasal carcinoma and was treated with a chemotherapy protocol of carboplatin and piroxicam. This report confirms the effectiveness of combination chemotherapy only without radiotherapy in a dog with nasal carcinoma and provides a guideline for providing alternative treatment.
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KEYWORD
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carboplatin, combination chemotherapy, nasal carcinoma, piroxicam
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